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Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer.

Authors
  • Sack, Ulrike1
  • Walther, Wolfgang
  • Scudiero, Dominic
  • Selby, Mike
  • Kobelt, Dennis
  • Lemm, Margit
  • Fichtner, Iduna
  • Schlag, Peter M
  • Shoemaker, Robert H
  • Stein, Ulrike
  • 1 Max-Delbrück-Center for Molecular Medicine, Berlin, Germany. , (Germany)
Type
Published Article
Journal
JNCI Journal of the National Cancer Institute
Publisher
Oxford University Press
Publication Date
Jul 06, 2011
Volume
103
Issue
13
Pages
1018–1036
Identifiers
DOI: 10.1093/jnci/djr190
PMID: 21685359
Source
Medline
License
Unknown

Abstract

Niclosamide inhibits S100A4-induced metastasis formation in a mouse model of colon cancer and has therapeutic potential.

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