A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia.
Department of Internal Medicine, University of Florida, Gainesville, FL, USA.
Department of Internal Medicine, University of Central Florida, Orlando, FL, USA.
Cancer Specialists of North Florida, Saint Augustine, FL, USA.
Division of Hematology and Oncology, Department of Internal Medicine, University of Florida, Gainesville, FL, USA.
- Published Article
Case Reports in Oncological Medicine
- Publication Date
Jan 01, 2016
Introduction. Ibrutinib is commonly used for the treatment of patients with CLL in either first-line or relapsed/refractory settings. Case Presentation. We present the case of a 74-year-old Caucasian man with CLL who presented with penile gangrene upon initiation of ibrutinib treatment. Our case is the first showing the complication of penile gangrene associated with ibrutinib use. The gangrene was self-limited upon discontinuing ibrutinib. Conclusion. Our finding describes a very rare yet important adverse event associated with ibrutinib use.
Report this publication
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 07/07/2017 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/27999696