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A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia.

Authors
  • Skelton Iv, William Paul1
  • Akhavan, Neeka N1
  • Taylor, Zachary A1
  • Nguyen, Thu-Cuc2
  • Hassan, Hassan3
  • Townsend, Tabitha N4
  • Pathak, Prajwol4
  • Trikha, Gaurav4
  • Dang, Nam H4
  • Dang, Long H4
  • Ali, Azka1
Type
Published Article
Journal
Case Reports in Oncological Medicine
Publisher
Hindawi Limited
Publication Date
Jan 01, 2016
Volume
2016
Pages
6980198–6980198
Identifiers
DOI: 10.1155/2016/6980198
PMID: 27999696
Source
Medline
License
Unknown

Abstract

Introduction. Ibrutinib is commonly used for the treatment of patients with CLL in either first-line or relapsed/refractory settings. Case Presentation. We present the case of a 74-year-old Caucasian man with CLL who presented with penile gangrene upon initiation of ibrutinib treatment. Our case is the first showing the complication of penile gangrene associated with ibrutinib use. The gangrene was self-limited upon discontinuing ibrutinib. Conclusion. Our finding describes a very rare yet important adverse event associated with ibrutinib use.

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