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Novel biomarkers of bladder decompensation after partial bladder obstruction.

Authors
  • Guven, Ahmet
  • Kalorin, Carmin
  • Onal, Bulent
  • Whitbeck, Catherine
  • Chichester, Paul
  • Kogan, Barry A
  • Levin, Robert M
  • Mannikarottu, Anita
Type
Published Article
Journal
Neurourology and urodynamics
Publication Date
Jan 01, 2007
Volume
26
Issue
7
Pages
1036–1042
Identifiers
PMID: 17487873
Source
Medline
License
Unknown

Abstract

This study shows that prolonged PBOO causes progressive deterioration in the rabbit bladder with decompensation after 8 weeks. Markedly decreased nerve density and severely reduced SOD and CAT activities are associated with the shift from compensated to decompensated function of the bladder. They may be excellent biomarkers of decompensation.

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