Affordable Access

Novel Application of Cellulose Paper As a Platform for the Macromolecular Self-Assembly of Biomimetic Giant Liposomes.

Authors
  • Kresse, Kayleigh M1
  • Xu, Melissa1
  • Pazzi, Joseph1
  • García-Ojeda, Marcos1
  • Subramaniam, Anand Bala1
  • 1 School of Engineering and §School of Natural Sciences, University of California , Merced, California 95343, United States. , (United States)
Type
Published Article
Journal
ACS Applied Materials & Interfaces
Publisher
American Chemical Society
Publication Date
Nov 30, 2016
Volume
8
Issue
47
Pages
32102–32107
Identifiers
PMID: 27933839
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

We report a facile and scalable method to fabricate biomimetic giant liposomes by using a cellulose paper-based materials platform. Termed PAPYRUS for Paper-Abetted liPid hYdRation in aqUeous Solutions, the method is general and can produce liposomes in various aqueous media and at elevated temperatures. Encapsulation of macromolecules and production of liposomes with membranes of complex compositions is straightforward. The ease of manipulation of paper makes practical massive parallelization and scale-up of the fabrication of giant liposomes, demonstrating for the first time the surprising usefulness of paper as a platform for macromolecular self-assembly.

Report this publication

Statistics

Seen <100 times