We study several aspects of generalized Janus configuration, which includes a theta term. We investigate the vacuum structure of the theory and find that unlike the Janus configuration without theta term there is no nontrivial vacuum. We also discuss BPS soliton configuration both by supersymmetry analysis and from energy functional. The half BPS configurations could be realized by introducing transverse (p,q)-strings in original brane configuration corresponding to generalized Janus configuration. It turns out the BPS soliton could be taken as modified dyon. We discuss the solution of half BPS equations for the sharp interface case. Moreover we construct less supersymmetric Janus configuration with theta term.