Affordable Access

Access to the full text

Notch signaling, the segmentation clock, and the patterning of vertebrate somites

Authors
  • Lewis, Julian1
  • Hanisch, Anja1
  • Holder, Maxine1
  • 1 Cancer Research UK London Research Institute, Vertebrate Development Laboratory, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK , London
Type
Published Article
Journal
Journal of Biology
Publisher
BioMed Central
Publication Date
May 22, 2009
Volume
8
Issue
4
Identifiers
DOI: 10.1186/jbiol145
Source
Springer Nature
Keywords
License
Yellow

Abstract

The Notch signaling pathway has multifarious functions in the organization of the developing vertebrate embryo. One of its most fundamental roles is in the emergence of the regular pattern of somites that will give rise to the musculoskeletal structures of the trunk. The parts it plays in the early operation of the segmentation clock and the later definition and differentiation of the somites are beginning to be understood.

Report this publication

Statistics

Seen <100 times