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Notch Signaling Affects Oral Neoplasm Cell Differentiation and Acquisition of Tumor-Specific Characteristics

Authors
  • nakano, keisuke
  • takabatake, kiyofumi
  • kawai, hotaka
  • yoshida, saori
  • maeda, hatsuhiko
  • kawakami, toshiyuki
  • nagatsuka, hitoshi
Publication Date
Apr 23, 2019
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

mesenchymal interactions and may be related to tumor development and tumorigenesis. This signaling may also be associated with the malignant transformation of ameloblastomas. Overall, Notch signaling appears to play a major role in the formation of the characteristic cellular composition and histological features of oral neoplasms, and this involvement has been reviewed here.

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