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Normalization of retinal vascular permeability in experimental diabetes with genistein.

Authors
  • Nakajima, M
  • Cooney, M J
  • Tu, A H
  • Chang, K Y
  • Cao, J
  • Ando, A
  • An, G J
  • Melia, M
  • de Juan, E Jr
Type
Published Article
Journal
Investigative Ophthalmology & Visual Science
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Publication Date
Aug 01, 2001
Volume
42
Issue
9
Pages
2110–2114
Identifiers
PMID: 11481279
Source
Medline
License
Unknown

Abstract

Long-term oral administration of genistein significantly inhibits retinal vascular leakage in experimentally induced diabetic rats. Tyrosine kinase inhibition may be a useful pharmacological approach for the treatment of diabetic-induced retinal vascular leakage.

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