Affordable Access

Nonsteroidal anti-inflammatory drugs and renal disease.

Authors
  • Fox, D A
  • Jick, H
Type
Published Article
Journal
JAMA
Publication Date
Mar 09, 1984
Volume
251
Issue
10
Pages
1299–1300
Identifiers
PMID: 6700026
Source
Medline
License
Unknown

Abstract

The relationship between nonsteroidal anti-inflammatory drugs (NSAIDs) and deterioration of renal function was examined in a large group of hospitalized patients carefully monitored for adverse drug effects and in a large group of outpatients whose discharge diagnoses after subsequent hospital admission were recorded. In the in-hospital study, no association between the use of NSAIDs and drug-attributed elevation of serum urea nitrogen levels diagnosed during hospitalization was present. In the outpatient study, none of the patients who used NSAIDs was hospitalized for acute renal disease. The majority of the available data related to indomethacin, ibuprofen, and phenylbutazone.

Report this publication

Statistics

Seen <100 times