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Noninvasive diagnosis of oral neoplasia based on fluorescence spectroscopy and native tissue autofluorescence.

Authors
  • Gillenwater, A
  • Jacob, R
  • Ganeshappa, R
  • Kemp, B
  • El-Naggar, A K
  • Palmer, J L
  • Clayman, G
  • Mitchell, M F
  • Richards-Kortum, R
Type
Published Article
Journal
Archives of otolaryngology--head & neck surgery
Publication Date
Nov 01, 1998
Volume
124
Issue
11
Pages
1251–1258
Identifiers
PMID: 9821929
Source
Medline
License
Unknown

Abstract

Consistent differences exist between the fluorescence spectra of abnormal and normal oral mucosa. Therefore, fluorescence spectroscopy has the potential to improve the noninvasive diagnosis of oral cavity neoplasia. Further studies will better define the role of this technique in the detection of premalignant and early oral cancer lesions.

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