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[Noninvasive brush biopsy as an innovative tool for early detection of oral carcinomas].

Authors
  • Remmerbach, T W
  • Mathes, S N
  • Weidenbach, H
  • Hemprich, A
  • Böcking, A
Type
Published Article
Journal
Mund-, Kiefer- und Gesichtschirurgie : MKG
Publication Date
Jul 01, 2004
Volume
8
Issue
4
Pages
229–236
Identifiers
PMID: 15293118
Source
Medline
License
Unknown

Abstract

The application of DNA image cytometry with DNA aneuploidy as a marker for neoplastic transformation in oral smears secures cytologic diagnosis of carcinomas. Smears from brushings of all visible oral lesions are an easily practicable, cheap, noninvasive, painless, and safe screening method for detection of oral precancerous lesions and squamous cell carcinoma in all stages. We conclude that DNA image cytometry is a very sensitive and highly specific, objective, and reproducible adjuvant tool for identification of neoplastic cells in oral smears.

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