Non-canonical programmed cell death mechanisms triggered by natural compounds
- Authors
- Type
- Published Article
- Journal
- Seminars in Cancer Biology
- Publisher
- Elsevier
- Publication Date
- Oct 23, 2016
- Volume
- 40-41
- Identifiers
- DOI: 10.1016/j.semcancer.2016.06.001
- Source
- LBMCC
- License
- Green
Abstract
Natural compounds are the fundament of pharmacological treatments and more than 50% of all anticancer drugs are of natural origins or at least derived from scaffolds present in Nature. Over the last 25 years, molecular mechanisms triggered by natural anticancer compounds were investigated. Emerging research showed that molecules of natural origins are useful for both preventive and therapeutic purposes by targeting essential hallmarks and enabling characteristics described by Hanahan and Weinberg. Moreover, …