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Nodal signaling is required for closure of the anterior neural tube in zebrafish.

Authors
Type
Published Article
Journal
BMC Developmental Biology
1471-213X
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
7
Pages
126–126
Identifiers
PMID: 17996054
Source
Medline
License
Unknown

Abstract

This work helps establish a role for Nodal signals in neurulation, and suggests that defects in Nodal signaling could underlie human neural tube defects such as exencephaly, a fatal condition characterized by an open neural tube in the anterior brain.

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