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The NKT cell system: bridging innate and acquired immunity

Authors
  • Taniguchi, Masaru1
  • Seino, Ken-ichiro1
  • Nakayama, Toshinori1
  • 1 Laboratory for Immunoregulation, RIKEN Research Center for Allergy and Immunology, Tsurumi, Graduate School of Medicine, Chiba University, Chiba, Japan , Chiba (Japan)
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
Dec 01, 2003
Volume
4
Issue
12
Pages
1164–1165
Identifiers
DOI: 10.1038/ni1203-1164
Source
Springer Nature
License
Yellow

Abstract

Although natural killer T cells are activated during infection, it is not clear how this process occurs. Closer examination indicates that recognition of endogenous ligands and interleukin 12, rather than bacterial products, may drive the activation process.

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