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[Nitric oxide donors, a new treatment for insulin resistance, metabolic syndrome and diabetes?].

Authors
  • Jayet, Pierre-Yves
  • Thalmann, Sébastien
  • Cook, Stéphane
  • Duplain, Hervé
  • Sartori, Claudio
  • Vollenweider, Peter
  • Scherrer, Urs
Type
Published Article
Journal
Revue médicale de la Suisse romande
Publication Date
Oct 01, 2004
Volume
124
Issue
10
Pages
642–644
Identifiers
PMID: 15573511
Source
Medline
License
Unknown

Abstract

Obesity/insulin resistance ("diabesity") and the associated long term complications are reaching epidemic proportions worldwide. Recent evidence in experimental animals and humans shows that nitric oxide (NO) plays a key role in glucose and cardiovascular homeostasis. Pharmaceutical drugs releasing small and physiological amounts of NO may represent potential new treatments for insulin resistance.

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