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Nitrate reductase assay using sodium nitrate for rapid detection of multidrug resistant tuberculosis.

Authors
  • Macedo, Maíra Bidart
  • Groll, Andrea Von
  • Fissette, Krista
  • Palomino, Juan Carlos
  • da Silva, Pedro Eduardo Almeida
  • Martin, Anandi
Type
Published Article
Journal
Brazilian Journal of Microbiology
Publisher
Elsevier
Publication Date
Jul 01, 2012
Volume
43
Issue
3
Pages
981–983
Identifiers
DOI: 10.1590/S1517-838220120003000019
PMID: 24031916
Source
Medline
Keywords
License
Unknown

Abstract

We validated the nitrate reductase assay (NRA) for the detection of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) using sodium nitrate (NaNO3) in replacement of potassium nitrate (KNO3) as nitrate source. NaNO3 is cheaper than KNO3 and has no restriction on use which facilitates the implementation of NRA to detect MDR-TB.

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