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NIR fluorescent ytterbium compound for in vivo fluorescence molecular imaging.

Authors
  • Aita, Kazuki
  • Temma, Takashi
  • Kuge, Yuji
  • Seki, Koh-ichi
  • Saji, Hideo
Type
Published Article
Journal
Luminescence : the journal of biological and chemical luminescence
Publication Date
Jan 01, 2010
Volume
25
Issue
1
Pages
19–24
Identifiers
DOI: 10.1002/bio.1136
PMID: 19484718
Source
Medline
License
Unknown

Abstract

We have developed a new NIR fluorescent probe based on an ytterbium(III) (E)-1-(pyridin-2-yl-diazenyl)naphthalen-2-ol (PAN) complex. This probe emits near-infrared luminescence derived from the Yb ion through excitation of the PAN moiety with visible light (lambda(ex)= 530 nm, lambda(em)= 975 nm). The results support the possible utility of the probe for in vivo fluorescence molecular imaging.

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