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Nifedipine-induced coronary vasodilation in ischemic hearts is attributable to bradykinin- and NO-dependent mechanisms in dogs.

Authors
  • Kitakaze, M
  • Asanuma, H
  • Takashima, S
  • Minamino, T
  • Ueda, Y
  • Sakata, Y
  • Asakura, M
  • Sanada, S
  • Kuzuya, T
  • Hori, M
Type
Published Article
Journal
Circulation
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Jan 25, 2000
Volume
101
Issue
3
Pages
311–317
Identifiers
PMID: 10645928
Source
Medline
License
Unknown

Abstract

These results indicate that the calcium channel blocker nifedipine mediates coronary vasodilation and improves myocardial ischemia through both bradykinin/NO-dependent and -independent mechanisms.

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