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NF-kappaB activation in light-induced retinal degeneration in a mouse model.

Authors
  • Wu, Tinghuai
  • Chen, Yueguo
  • Chiang, Samuel K S
  • Tso, Mark O M
Type
Published Article
Journal
Investigative Ophthalmology & Visual Science
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Publication Date
Sep 01, 2002
Volume
43
Issue
9
Pages
2834–2840
Identifiers
PMID: 12202499
Source
Medline
License
Unknown

Abstract

Intense light activated NF-kappaB in the photoreceptor cells in vivo, increased the NF-kappaB DNA-binding activity, and increased the expression of mRNA of IkappaBalpha, a target gene of NF-kappaB.

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