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A new type D retrovirus isolated from macaques with an immunodeficiency syndrome.

Authors
  • Daniel, M D
  • King, N W
  • Letvin, N L
  • Hunt, R D
  • Sehgal, P K
  • Desrosiers, R C
Type
Published Article
Journal
Science (New York, N.Y.)
Publication Date
Feb 10, 1984
Volume
223
Issue
4636
Pages
602–605
Identifiers
PMID: 6695172
Source
Medline
License
Unknown

Abstract

Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).

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