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A new turn on Pd(2+)-specific fluorescence probe and its use as an imaging reagent for cellular uptake in Hct116 cells.

Authors
  • Reddy G, Upendar
  • Ali, Firoj
  • Taye, Nandaraj
  • Chattopadhyay, Samit
  • Das, Amitava
Type
Published Article
Journal
Chemical Communications
Publisher
The Royal Society of Chemistry
Publication Date
Feb 28, 2015
Volume
51
Issue
17
Pages
3649–3652
Identifiers
DOI: 10.1039/c4cc10171e
PMID: 25644119
Source
Medline
License
Unknown

Abstract

A new coumarin-rhodamine conjugate is used as a specific probe for Pd(2+) ions and this could even delineate Pd(II) from Pd(0) or Pd(IV) in aqueous buffer medium (pH ∼ 7). Laser confocal microscopic studies reveal that efficient cellular internalization of this reagent helps in imaging the cellular uptake of Pd(2+) as low as 0.1 ppm in Hct 116 cells. This reagent could even be used for estimation of Pd(2+) in human urine samples.

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