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New surgical approach to overcome the inability of injured mammalian axons to grow within their environment.

Authors
  • Solomon, A
  • Lavie, V
  • Ben-Bassat, S
  • Belkin, M
  • Schwartz, M
Type
Published Article
Journal
Journal of Neural Transplantation and Plasticity
Publisher
Hindawi Limited
Publication Date
Jan 01, 1991
Volume
2
Issue
3-4
Pages
243–248
Identifiers
PMID: 1782256
Source
Medline
License
Unknown

Abstract

We present a new method for creating conditions conductive to axonal growth in injured optic nerves of adult rabbits. The surgical approach consists of making a cavity in the adult rabbit optic nerve, into which a piece of nitrocellulose soaked with conditioned medium originating from regenerating fish optic nerves is implanted. In addition, daily irradiation (10 days, 5 min, 35 mW) with low energy He-Ne laser is carried out. Such a combined treatment may open a door to neurobiologists and clinicians, hoping to unravel the enigma of mammalian CNS regeneration.

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