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[A new real-time method monitoring behaviors of living cells in vitro-PCC].

Authors
  • Wei, Xiaolan
  • Mo, Zhihong
Type
Published Article
Journal
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Publication Date
Oct 01, 2006
Volume
23
Issue
5
Pages
1145–1148
Identifiers
PMID: 17121374
Source
Medline
License
Unknown

Abstract

A method combinating piezoelectric-biochip technique with cell culture technique in vitro has been developed. Piezoelectric cell-based chip (PCC) can continously monitor the behaviors of living cells attached to or spreaded on surfaces. The method measures the resonant frequency (f), the dissipation energy (D) and impedance (Z), in real time. These multi parameters can inflect information of cells qualitively and quantitively. This paper covers principle, materials and methods, results and discussion of the new technique, simultaniously indicates its application and trends.

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