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A new method of histologic dating of human endometrium in the luteal phase.

Authors
  • Li, T C
  • Rogers, A W
  • Dockery, P
  • Lenton, E A
  • Cooke, I D
Type
Published Article
Journal
Fertility and Sterility
Publisher
Elsevier
Publication Date
Jul 01, 1988
Volume
50
Issue
1
Pages
52–60
Identifiers
PMID: 3289976
Source
Medline
License
Unknown

Abstract

Morphometric analysis was performed on 70 endometrial biopsy specimens collected from a population of fertile women. Of the 17 morphometric measurements that were performed on each endometrial biopsy, only 5 were required to achieve a highly significant correlation with chronologic dating based on luteinizing hormone surge (R = 0.99). The result of histologic dating, based on morphometric analysis of endometrial biopsies collected from a separate, unbiased population, correlated strongly and significantly with chronologic dating (r = 0.98, P less than 0.0001). The correlation was better than that achieved when histologic dating was performed according to the conventional dating criteria (r = 0.88, P less than 0.001).

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