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A new method for the determination of steroid sulphatase activity in leukocytes in X-linked recessive ichthyosis.

Authors
  • Jöbsis, A C
  • De Groot, W P
  • Meijer, A E
  • Van der Loos, C M
Type
Published Article
Journal
The British journal of dermatology
Publication Date
May 01, 1983
Volume
108
Issue
5
Pages
567–572
Identifiers
PMID: 6573909
Source
Medline
License
Unknown

Abstract

The diagnosis of X-linked ichthyosis can now be reliably established by using a non-radioactive method to detect steroid sulphatase deficiency in leukocytes. This new method yields the same results with leukocytes as with cultured fibroblasts. The second type of microsomal arylsulphatase previously described in cultured fibroblasts is also present in leukocytes.

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