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[A new method of bone sterilization].

Authors
  • Jerosch, J
  • Preisendanz, H
  • Krumschmidt, H
  • Castro, W H
Type
Published Article
Journal
Biomedizinische Technik. Biomedical engineering
Publication Date
May 01, 1989
Volume
34
Issue
5
Pages
117–120
Identifiers
PMID: 2660915
Source
Medline
License
Unknown

Abstract

Bone transplantation is associated with two major problems: the sterility in particular with respect to HIV, and the osteoinductivity of the transplant. We describe a procedure which sterilizes the graft while keeping the osteoinductive potential of the bone. After harvesting the material the bone is immediately deep frozen (-80 degrees C), and then freeze dried. To sterilize the bone it is treated with gamma-radiation at a dose of 2.5 Mrad in an argon atmosphere. All grafts are subsequently stored in argon at -80 degrees C.

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