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A new method for absolute quantitation of MRS metabolites.

Authors
  • Barantin, L
  • Le Pape, A
  • Akoka, S
Type
Published Article
Journal
Magnetic resonance in medicine
Publication Date
Aug 01, 1997
Volume
38
Issue
2
Pages
179–182
Identifiers
PMID: 9256094
Source
Medline
License
Unknown

Abstract

A new method for absolute quantitation of MRS spectra is presented. This method is not based on a reference peak, derived from a real NMR signal, but rather on a synthesized NMR reference produced by an electronic device, transmitted by a broad-band antenna to avoid quality factor variations. This signal is therefore received at the same time as the sample signal. The reference line produced is stable in time (maximum variation lower than 2%) and allows precise and accurate measurement of absolute concentrations (mean error lower than 3%) in vitro and in vivo.

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