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New knowledge in primary biliary cirrhosis.

Authors
  • Gershwin, M E
  • Mackay, I R
Type
Published Article
Journal
Hospital practice (1995)
Publication Date
Aug 15, 1995
Volume
30
Issue
8
Pages
29–36
Identifiers
PMID: 7543484
Source
Medline
License
Unknown

Abstract

The autoantibodies characteristic of the disease react against mitochondrial enzymes essential to the function of all body cells, yet the disease is highly focused on only one tissue: the epithelial lining of intrahepatic bile ductules. The explanation may lie in tissue-specific cell-surface expression of a triggering antigen.

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