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A new characteristic karyotypic anomaly in lymphoproliferative disorders

Authors
  • Van den Berghe, Herman; 5147;
  • Parloir, C;
  • David, Guido; 18747;
  • Michaux, JL;
  • Sokal, G;
Publication Date
Jul 01, 1979
Source
Lirias
Keywords
Language
English
License
Unknown
External links

Abstract

A new characteristic chromosome anomaly t(11;14)(q14;q32?) in lymphoproliferative disorders (LPD) is described in 4 cases. The extra material was found on a "14 chromosome (14q+) and belonged to the long arm of one "11 chromosome in 3 cases and to the long arm of a "14 in the other case. These cases confirm that the distal end of chromosome 14q may function as a "receptor site," according to the hypothesis of Kaiser-McCaw et al. and also tend to indicate that chromosome "14 may not be unique in showing so-called "donor" and "receptor sites," and that other chromosomes, in casu chromosome "11, may behave similarly. / status: published

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