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A new asteltoxin analog with insecticidal activity from Pochonia suchlasporia TAMA 87

Authors
  • Suminto, Syaefudin1
  • Takatsuji, Eri1
  • Iguchi, Ayako1
  • Kanzaki, Hiroshi1
  • Okuda, Toru2
  • Nitoda, Teruhiko1
  • 1 Graduate School of Environmental and Life Science, Okayama University, Okayama 700–8530, Japan
  • 2 HyphaGenesis Inc., Tokyo 194–0041, Japan
Type
Published Article
Journal
Journal of Pesticide Science
Publisher
Pesticide Science Society of Japan
Publication Date
May 20, 2020
Volume
45
Issue
2
Pages
81–85
Identifiers
DOI: 10.1584/jpestics.D19-081
PMID: 32508514
PMCID: PMC7251201
Source
PubMed Central
Keywords
License
Unknown

Abstract

A new asteltoxin analog, named asteltoxin H ( 1 ), was isolated by the solid-state fermentation of the fungus Pochonia suchlasporia var. suchlasporia TAMA 87. The chemical structure of 1 was deduced by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and UV-Vis analyses. Compound 1 showed insecticidal activity against prepupae of the blowfly, Lucilia sericata , with an LD50 value of 0.94 µg/mg prepupal body weight.

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