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A new approach to the synthesis of efaroxan.

Authors
  • Couture, K
  • Gouverneur, V
  • Mioskowski, C
Type
Published Article
Journal
Bioorganic & Medicinal Chemistry Letters
Publisher
Elsevier
Publication Date
Oct 18, 1999
Volume
9
Issue
20
Pages
3023–3026
Identifiers
PMID: 10571168
Source
Medline
License
Unknown

Abstract

Efaroxan was synthetised by cyclisation of the tertiary alcohol 2 which was prepared by the ring opening of the gem-disubstituted epoxide 3 with ortho-metallated fluorobenzene.

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