Affordable Access

deepdyve-link
Publisher Website

A new 3D printed radial flow-cell for chemiluminescence detection: Application in ion chromatographic determination of hydrogen peroxide in urine and coffee extracts.

Authors
  • Gupta, Vipul1
  • Mahbub, Parvez2
  • Nesterenko, Pavel N2
  • Paull, Brett3
  • 1 Australian Centre for Research on Separation Science (ACROSS), School of Physical Sciences, University of Tasmania, Sandy Bay, Hobart 7001, Tasmania, Australia; ARC Centre of Excellence for Electromaterials Science, School of Physical Sciences, University of Tasmania, Sandy Bay, Hobart 7001, Tasmania, Australia. , (Australia)
  • 2 Australian Centre for Research on Separation Science (ACROSS), School of Physical Sciences, University of Tasmania, Sandy Bay, Hobart 7001, Tasmania, Australia. , (Australia)
  • 3 Australian Centre for Research on Separation Science (ACROSS), School of Physical Sciences, University of Tasmania, Sandy Bay, Hobart 7001, Tasmania, Australia; ARC Centre of Excellence for Electromaterials Science, School of Physical Sciences, University of Tasmania, Sandy Bay, Hobart 7001, Tasmania, Australia. Electronic address: [email protected] , (Australia)
Type
Published Article
Journal
Analytica chimica acta
Publication Date
Apr 16, 2018
Volume
1005
Pages
81–92
Identifiers
DOI: 10.1016/j.aca.2017.12.039
PMID: 29389322
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

A new polymer flow-cell for chemiluminescence detection (CLD) has been designed and developed by diverging multiple linear channels from a common centre port in a radial arrangement. The fabrication of radial flow-cell by 3D PolyJet printing and fused deposition modeling (FDM) has been evaluated, and compared with a similarly prepared spiral flow-cell design commonly used in chemiluminescence detectors. The radial flow-cell required only 10 h of post-PolyJet print processing time as compared to ca. 360 h long post-PolyJet print processing time required for the spiral flow-cell. Using flow injection analysis, the PolyJet 3D printed radial flow-cell provided an increase in both the signal magnitude and duration, with an average increase in the peak height of 63% and 58%, peak area of 89% and 90%, and peak base width of 41% and 42%, as compared to a coiled-tubing spiral flow-cell and the PolyJet 3D printed spiral flow-cell, respectively. Computational fluid dynamic (CFD) simulations were applied to understand the origin of the higher CLD signal obtained with the radial flow-cell design, indicating higher spatial coverage near the inlet and lower linear velocities in the radial flow-cell. The developed PolyJet 3D printed radial flow-cell was applied in a new ion chromatography chemiluminescence based assay for the detection of H2O2 in urine and coffee extracts. Copyright © 2018 Elsevier B.V. All rights reserved.

Report this publication

Statistics

Seen <100 times