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Neutrophil myeloperoxidase measurements in plasma, laminar tissue, and skin of horses given black walnut extract.

Authors
  • Riggs, Laura M
  • Franck, Thierry
  • Moore, James N
  • Krunkosky, Thomas M
  • Hurley, David J
  • Peroni, John F
  • de la Rebière, Geoffroy
  • Serteyn, Didier A
Type
Published Article
Journal
American Journal of Veterinary Research
Publisher
American Veterinary Medical Association
Publication Date
Jan 01, 2007
Volume
68
Issue
1
Pages
81–86
Identifiers
PMID: 17199423
Source
Medline
License
Unknown

Abstract

In horses, BWHE administration causes increases in MPO concentration and activity in laminar tissue and skin and the time of increased MPO concentration correlates with emigration of WBCs from the vasculature. These findings support the hypothesis that activation of peripheral WBCs is an early step in the pathogenesis of acute laminitis.

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