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Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status.

Authors
  • Haase-Fielitz, Anja
  • Haase, Michael
  • Devarajan, Prasad
Type
Published Article
Journal
Annals of Clinical Biochemistry International Journal of Laboratory Medicine
Publisher
SAGE Publications
Publication Date
May 01, 2014
Volume
51
Issue
Pt 3
Pages
335–351
Identifiers
DOI: 10.1177/0004563214521795
PMID: 24518531
Source
Medline
Keywords
License
Unknown

Abstract

We identified several studies that collectively strongly support the use of NGAL as a biomarker for the prediction of AKI. However, we noted some limitations, including lack of published studies that adhere to diagnostic study guidelines, heterogeneity in AKI definition, the lack of uniformly applicable cut-off values and variability in the performance of commercially available NGAL assays.

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