Affordable Access

deepdyve-link
Publisher Website

Neurovascular injury in acute hyperglycemia and diabetes: A comparative analysis in experimental stroke.

Authors
  • Elgebaly, Mostafa M1
  • Ogbi, Safia
  • Li, Weiguo
  • Mezzetti, Erin M
  • Prakash, Roshini
  • Johnson, Maribeth H
  • Bruno, Askiel
  • Fagan, Susan C
  • Ergul, Adviye
  • 1 Program in Clinical and Experimental Therapeutics, Department of Clinical and Administrative Pharmacy, College of Pharmacy, University of Georgia; MCG, UGA Clinical Pharmacy Program, HM-1200, Augusta, GA, 30912, USA. , (Georgia)
Type
Published Article
Journal
Translational stroke research
Publication Date
Sep 01, 2011
Volume
2
Issue
3
Pages
391–398
Identifiers
DOI: 10.1007/s12975-011-0083-3
PMID: 21909340
Source
Medline
License
Unknown

Abstract

The finding that functional outcome is poorer in both acute HG and diabetes without a significant increase in infarct size suggests that amplified vascular damage contributes to neurological deficit in hyperglycemia. These results highlight the importance of vascular protection to improve neurological outcome in acute ischemic stroke.

Report this publication

Statistics

Seen <100 times