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Neuropilin-1 is overexpressed in osteosarcoma and contributes to tumor progression and poor prognosis.

Authors
  • 1
  • 1 Orthopaedics Department, Xuhui Central Hospital, No.966, Middle Huaihai Road, Shanghai, 200031, China. , (China)
Type
Published Article
Journal
Clinical & Translational Oncology
1699-3055
Publisher
Springer-Verlag
Publication Date
Volume
16
Issue
8
Pages
732–738
Identifiers
DOI: 10.1007/s12094-013-1141-y
PMID: 24338507
Source
Medline
License
Unknown

Abstract

This is the first study to reveal that NRP-1 overexpression may be related to the prediction of metastasis potency, response to chemotherapy and poor prognosis for osteosarcoma patients, suggesting that NRP-1 may serve as a prognostic marker for the optimization of clinical treatments.

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