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Neuropeptide Y modulates effects of bradykinin and prostaglandin E2 on trigeminal nociceptors via activation of the Y1 and Y2 receptors.

Authors
Type
Published Article
Journal
British journal of pharmacology
Publication Date
Volume
150
Issue
1
Pages
72–79
Identifiers
PMID: 17143304
Source
Medline
License
Unknown

Abstract

These results demonstrate that NPY modulation of peptidergic neurons is due to net activation of inhibitory Y1 and excitatory Y2 receptor systems. The relative expression or activity of these opposing receptor systems may mediate dynamic responses to injury and pain.

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