Affordable Access

deepdyve-link
Publisher Website

[Neuromyelitis optica spectrum: novel concept of pathogenesis, diagnosis and treatment of Devic's disease].

Authors
  • Csécsei, Péter
  • Trauninger, Anita
  • Komoly, Sámuel
  • Illés, Zsolt
Type
Published Article
Journal
Orvosi hetilap
Publication Date
Nov 15, 2009
Volume
150
Issue
46
Pages
2101–2109
Identifiers
DOI: 10.1556/OH.2009.28724
PMID: 19889597
Source
Medline
License
Unknown

Abstract

The identification of autoantibodies generated against the brain isoform water channel aquaporin4 in the sera of patients, changed the current diagnostic guidelines and concept of neuromyelitis optica (NMO). In a number of cases, clinical manifestation is spatially limited to myelitis or relapsing optic neuritis creating a diverse. NMO spectrum. Since prevention of relapses provides the only possibility to reduce permanent disability, early diagnosis and treatment is mandatory. In the present study, we discuss the potential role of neuroimaging and laboratory tests in differentiating the NMO spectrum from other diseases, as well as the diagnostic procedures and therapeutic options. We also present clinical cases, to provide examples of different clinical settings, diagnostic procedures and therapeutic decisions.

Report this publication

Statistics

Seen <100 times