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Neuromodulation attenuates bladder hyperactivity in a rat cystitis model.

Authors
  • Su, Xin
  • Nickles, Angela
  • Nelson, Dwight E
Type
Published Article
Journal
BMC Urology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2013
Volume
13
Pages
70–70
Identifiers
DOI: 10.1186/1471-2490-13-70
PMID: 24314228
Source
Medline
License
Unknown

Abstract

Using continuous flow cystyometry, we find that SN stimulation can produce effects on micturition consistent with its effects on isovolumetric model, and consistent with the therapeutic effect observed with InterStim® therapy in overactive bladder patients. Although the effect of SN stimulation was slightly greater in bladder irritated over normal rats, the difference was not statistically significant.

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