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Neuroanatomy and physiology of colorectal function and defaecation: from basic science to human clinical studies.

Authors
  • Brookes, S J
  • Dinning, P G
  • Gladman, M A
Type
Published Article
Journal
Neurogastroenterology & Motility
Publisher
Wiley (Blackwell Publishing)
Publication Date
Dec 01, 2009
Volume
21 Suppl 2
Pages
9–19
Identifiers
DOI: 10.1111/j.1365-2982.2009.01400.x
PMID: 19824934
Source
Medline
License
Unknown

Abstract

Colorectal physiology is complex and involves programmed, coordinated interaction between muscular and neuronal elements. Whilst a detailed understanding remains elusive, novel information has emerged from recent basic science and human clinical studies concerning normal sensorimotor mechanisms and the organization and function of the key elements involved in the control of motility. This chapter summarizes these observations to provide a contemporary review of the neuroanatomy and physiology of colorectal function and defaecation.

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