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Nesfatin-1 Hormone Levels in Patients with Antisocial Personality Disorder and Their Relationship with Clinical Variables.

Authors
  • Kaya, Şüheda1
  • Özsoy, Filiz2
  • Taşcı, Gülay3
  • Kalaycı, Mehmet3
  • 1 Elazığ Mental Health and Diseases Hospital, Elazığ, Turkey. , (Turkey)
  • 2 Department of Psychiatry, Tokat State Hospital, Tokat, Turkey. , (Turkey)
  • 3 Elazığ Fethi Sekin City Hospital, Elazığ, Turkey. , (Turkey)
Type
Published Article
Journal
Psychiatry investigation
Publication Date
Sep 01, 2020
Volume
17
Issue
9
Pages
889–895
Identifiers
DOI: 10.30773/pi.2020.0067
PMID: 32894929
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

This study aims to investigate the levels of nesfatin-1-hormone in patients with Antisocial Personality Disorder (ASPD) and their relationship with clinical variables. A total of 90 people (45 ASPD, 45 controls) were included in our study. Sociodemographic Data Form, Beck-Depression-Inventory (BDI), Beck-Anxiety-Inventory (BAI), Barratt Impulsivity Scale (BIS-11), Buss-Durkee-Hostility-Inventory (BDHI) were applied to all participants. Venous blood samples were taken from participants at the same time of the day when they were hungry. It was found that the BDI and BAI scores of the ASPD were higher than those of the controls (p<0.001, for both scales). The scores in BIS-11; motor and nonplanning-impulsivity subscales were higher than those of the controls (p<0.001, 0.036, respectively). The scores obtained by the ASPD were higher in all subscales of BDHI (p<0.001). For the nesfatin-1-hormone, the values of the ASPD were lower than those of the controls (p=0.044). No relationship was found between the nesfatin-1-hormone and any other laboratory parameters and applied scales (p>0.05). This is the first study to examine the nesfatin-1-hormone levels in patients with any personality disorder. Further studies with more participants are needed in different types of personality disorders to understand the relationship between personality disorder and nesfatin-1-hormone levels.

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