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[Nerve injury due to peripheral nerve blocks: Pathophysiology and aetiology].

Authors
  • Steinfeldt, Thorsten
Type
Published Article
Journal
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
Publication Date
May 01, 2012
Volume
47
Issue
5
Identifiers
DOI: 10.1055/s-0032-1313571
PMID: 22628029
Source
Medline
License
Unknown

Abstract

Permanent nerve injury as a complication of peripheral regional anaesthesia is fortunately rare with an estimated incidence of 0,03%. However, transient neurological symptoms are more frequent with an occurrence of 3-8%. The pathophysiology and etiology of nerve injury depends on a number of different factors. The needle-nerve trauma, cytotoxicity of local anaesthetics, patient factors (i.e. morbidity) and factors which are related to surgical interventions should be considered. Regarding pathophysiology, trauma-related inflammation should be acknowledged as an important interference during nerve recovery. Needle-nerve contacts, nerve perforation and local cytotoxicity of local anaesthetics should be reduced to a minimum by application of nerve stimulation, ultrasound and an adequate dosage of local anaesthetics with less locotoxicity.

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