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[Nerve fiber regeneration in preformed tissue spaces].

Authors
  • Dietzmann, K
  • Künnemann, J
  • Vitzthum, H E
Type
Published Article
Journal
Zentralblatt für allgemeine Pathologie u. pathologische Anatomie
Publication Date
Jan 01, 1990
Volume
136
Issue
6
Pages
579–585
Identifiers
PMID: 2281724
Source
Medline
License
Unknown

Abstract

Described in this paper is a new artificial chamber model to enable in vivo investigation of nerve fiber regeneration. Transection of the sciatic nerve of a rat was followed by analysis of axonal regeneration and revascularisation in the tissue chamber. Vascularisation of the endoneurium via the newly formed epineurium and perineurium was almost physiological in the cavity formed. The latter was found to be suitable for application of drugs and neurotrophic substances.

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