[Nerve fiber regeneration in preformed tissue spaces].
- Authors
- Type
- Published Article
- Journal
- Zentralblatt für allgemeine Pathologie u. pathologische Anatomie
- Publication Date
- Jan 01, 1990
- Volume
- 136
- Issue
- 6
- Pages
- 579–585
- Identifiers
- PMID: 2281724
- Source
- Medline
- License
- Unknown
Abstract
Described in this paper is a new artificial chamber model to enable in vivo investigation of nerve fiber regeneration. Transection of the sciatic nerve of a rat was followed by analysis of axonal regeneration and revascularisation in the tissue chamber. Vascularisation of the endoneurium via the newly formed epineurium and perineurium was almost physiological in the cavity formed. The latter was found to be suitable for application of drugs and neurotrophic substances.
