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Nephrogenic diabetes insipidus in a dog with intestinal leiomyosarcoma.

Authors
  • Cohen, M
  • Post, G S
Type
Published Article
Journal
Journal of the American Veterinary Medical Association
Publication Date
Dec 15, 1999
Volume
215
Issue
12
Identifiers
PMID: 10613214
Source
Medline
License
Unknown

Abstract

Nephrogenic diabetes insipidus was diagnosed in a dog with an intestinal leiomyosarcoma. The diagnosis of nephrogenic diabetes insipidus was made on the basis of results of serum biochemical tests, urinalyses, and a water-deprivation test, along with a lack of response to exogenous administration of vasopressin following the water-deprivation test. The temporal association between resection of the intestinal mass and resolution of clinical signs of diabetes insipidus (i.e., polyuria and polydipsia) and between recurrence of clinical signs and detection of metastatic disease suggests that there may have been a causal relationship, and nephrogenic diabetes insipidus may have developed as a paraneoplastic syndrome in this dog.

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