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Neoadjuvant chemotherapy is associated with prolonged primary treatment intervals in patients with advanced epithelial ovarian cancer.

Authors
  • Milam, Michael R
  • Tao, Xia
  • Coleman, Robert L
  • Harrell, Robyn
  • Bassett, Roland
  • Dos Reis, Ricardo
  • Ramirez, Pedro T
Type
Published Article
Journal
International Journal of Gynecological Cancer
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Jan 01, 2011
Volume
21
Issue
1
Pages
66–71
Identifiers
DOI: 10.1097/IGC.0b013e3182013e2f
PMID: 21178571
Source
Medline
License
Unknown

Abstract

In patients with advanced ovarian cancer, NC followed by abdominal hysterectomy is associated with improved perioperative outcomes including optimal cytoreduction, decreased blood loss, and decreased inpatient hospitalization. In this cohort, NC was also associated with prolonged chemotherapy treatment intervals and increased chemotherapy cycles without improvement in survival.

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