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Nearly a Third of High-Grade Dysplasia and Colorectal Cancer Is Undetected in Patients with Inflammatory Bowel Disease.

Authors
  • Eluri, Swathi1, 2
  • Parian, Alyssa M3
  • Limketkai, Berkeley N4, 5
  • Ha, Christina Y6, 7
  • Brant, Steven R3
  • Dudley-Brown, Sharon3
  • Efron, Jonathan E3
  • Fang, Sandy G3
  • Gearhart, Susan L3
  • Marohn, Michael R3
  • Meltzer, Stephen J3
  • Bashar, Safar3
  • Truta, Brindusa3
  • Montgomery, Elizabeth A3
  • Lazarev, Mark G3
  • 1 Division of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, 4119B Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC, 27599-7080, USA. [email protected]
  • 2 Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD, 21287, USA. [email protected]
  • 3 Division of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, 4119B Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC, 27599-7080, USA.
  • 4 Stanford University School of Medicine, Stanford, CA, USA.
  • 5 Digestive Health Liver Clinic, 900 Blake Wilbur Dr, MC 5355, Palo Alto, CA, 94304, USA.
  • 6 David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • 7 Ronald Reagan UCLA Medical Center, 757 Westwood Plaza, Los Angeles, CA, 90095, USA.
Type
Published Article
Journal
Digestive Diseases and Sciences
Publisher
Springer-Verlag
Publication Date
Dec 01, 2017
Volume
62
Issue
12
Pages
3586–3593
Identifiers
DOI: 10.1007/s10620-017-4652-5
PMID: 28631086
Source
Medline
Keywords
License
Unknown

Abstract

The prevalence of previously undetected HGD/CRC in IBD found at colectomy was 29%. The high proportion of undetected rectal and right-sided HGD/CRC suggests that these areas may need greater attention during surveillance.

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