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Nature of glomerular dysfunction in pre-eclampsia.

Authors
  • Lafayette, R A
  • Druzin, M
  • Sibley, R
  • Derby, G
  • Malik, T
  • Huie, P
  • Polhemus, C
  • Deen, W M
  • Myers, B D
Type
Published Article
Journal
Kidney international
Publication Date
Oct 01, 1998
Volume
54
Issue
4
Pages
1240–1249
Identifiers
PMID: 9767540
Source
Medline
License
Unknown

Abstract

The proportionate (approximately 40%) depression of Kf for single nephrons and GFR suggests that hypofiltration in PET does not have a hemodynamic basis, but is a consequence of structural changes that lead to impairment of intrinsic glomerular ultrafiltration capacity.

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