Affordable Access

deepdyve-link
Publisher Website

Nanotechnology Approaches in Chronic Wound Healing.

Authors
  • Blanco-Fernandez, Barbara1
  • Castaño, Oscar1, 2, 3, 4
  • Mateos-Timoneda, Miguel Ángel1, 3, 5
  • Engel, Elisabeth1, 3, 5
  • Pérez-Amodio, Soledad1, 3, 5
  • 1 Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain. , (Spain)
  • 2 Electronics and Biomedical Engineering, Universitat de Barcelona (UB), Barcelona, Spain. , (Spain)
  • 3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, Madrid, Spain. , (Spain)
  • 4 Bioelectronics Unit and Nanobioengineering Lab, Institute for Nanoscience and Nanotechnology of the University of Barcelona (IN2UB), Barcelona, Spain. , (Spain)
  • 5 Materials Science and Metallurgical Engineering, Polytechnic University of Catalonia (UPC), Barcelona, Spain. , (Spain)
Type
Published Article
Journal
Advances in wound care
Publication Date
May 01, 2021
Volume
10
Issue
5
Pages
234–256
Identifiers
DOI: 10.1089/wound.2019.1094
PMID: 32320364
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Significance: The incidence of chronic wounds is increasing due to our aging population and the augment of people afflicted with diabetes. With the extended knowledge on the biological mechanisms underlying these diseases, there is a novel influx of medical technologies into the conventional wound care market. Recent Advances: Several nanotechnologies have been developed demonstrating unique characteristics that address specific problems related to wound repair mechanisms. In this review, we focus on the most recently developed nanotechnology-based therapeutic agents and evaluate the efficacy of each treatment in in vivo diabetic models of chronic wound healing. Critical Issues: Despite the development of potential biomaterials and nanotechnology-based applications for wound healing, this scientific knowledge is not translated into an increase of commercially available wound healing products containing nanomaterials. Future Directions: Further studies are critical to provide insights into how scientific evidences from nanotechnology-based therapies can be applied in the clinical setting.

Report this publication

Statistics

Seen <100 times