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Nanotechnological approach to delivering nutraceuticals as promising drug candidates for the treatment of atherosclerosis.

Authors
  • Pillai, Sindhu C1
  • Borah, Ankita1
  • Jacob, Eden Mariam1
  • Kumar, D Sakthi1
  • 1 Bio-Nano Electronics Research Centre, Graduate School of Interdisciplinary New Science, Toyo University, Saitama, Japan. , (Japan)
Type
Published Article
Journal
Drug delivery
Publication Date
Dec 01, 2021
Volume
28
Issue
1
Pages
550–568
Identifiers
DOI: 10.1080/10717544.2021.1892241
PMID: 33703990
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Atherosclerosis is Caesar's sword, which poses a huge risk to the present generation. Understanding the atherosclerotic disease cycle would allow ensuring improved diagnosis, better care, and treatment. Unfortunately, a highly effective and safe way of treating atherosclerosis in the medical community remains a continuous challenge. Conventional treatments have shown considerable success, but have some adverse effects on the human body. Natural derived medications or nutraceuticals have gained immense popularity in the treatment of atherosclerosis due to their decreased side effects and toxicity-related issues. In hindsight, the contribution of nutraceuticals in imparting enhanced clinical efficacy against atherosclerosis warrants more experimental evidence. On the other hand, nanotechnology and drug delivery systems (DDS) have revolutionized the way therapeutics are performed and researchers have been constantly exploring the positive effects that DDS brings to the field of therapeutic techniques. It could be as exciting as ever to apply nano-mediated delivery of nutraceuticals as an additional strategy to target the atherosclerotic sites boasting high therapeutic efficiency of the nutraceuticals and fewer side effects.

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