Affordable Access

deepdyve-link
Publisher Website

Nanoscale delivery systems in treatment of posterior ocular neovascularization: strategies and potential applications.

Authors
  • Bhatt, Priyanka1
  • Kelly, Shannon1
  • Sutariya, Vijaykumar1
  • 1 Department of Pharmaceutical Sciences, Taneja College of Pharmacy, University of South Florida, 12901 Bruce B Downs Blvd, MDC 30, Tampa, FL 33612-4749, USA.
Type
Published Article
Journal
Therapeutic Delivery
Publisher
"Future Science, LTD"
Publication Date
Nov 01, 2019
Volume
10
Issue
11
Pages
737–747
Identifiers
DOI: 10.4155/tde-2019-0025
PMID: 31718481
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Pathologic posterior neovascularization of eye is a major cause of irreversible vision loss and limitations of therapeutics to be successfully delivered to back of the eye has been a main obstacle for its effective treatment. Current pharmacological treatment using anti-VEGF agents being delivered intravitreally are effective but complicated due to anatomical and physiological barriers, as well as administration of high and frequent doses. With expanding horizons of nanotechnology, it can be possible to formulate promising nanoscale delivery system to improve penetration and sustained the release of therapeutic in posterior segment of the eye. Taking into consideration advances in the field of nanoscale delivery systems, this special report focuses on emerging strategies and their applications for treatment of posterior ocular neovascularization.

Report this publication

Statistics

Seen <100 times